Computational modeling of frequency-dependent neocortical response to thalamic neurostimulation in epilepsy

Linda Iris Joseph Tomy, Elif Köksal-Ersöz, A. Nica, M. Yochum, P. Benquet, Fabrice Wendling

PLoS Computational Biology, 2025

Deep learning on high-density EEG during a cognitive task distinguishes patients with Parkinson's disease from healthy controls.

Y. Denoyer, J. Duprez, Jean-François Houvenaghel, Fabrice Wendling, P. Benquet

Journal of Neural Engineering, 2025

eCOALIA: Neocortical neural mass model for simulating electroencephalographic signals

E. K. Ersöz, M. Yochum, P. Benquet, Fabrice Wendling

SoftwareX, 2024

Expansion of epileptogenic networks via neuroplasticity in neural mass models

E. K. Ersöz, P. Benquet, F. Wendling

PLoS Comput. Biol., 2024

Localization of the epileptogenic network from scalp EEG using a patient-specific whole-brain model

M. Maliia, Elif Köksal-Ersöz, Adrien Bénard, Tristan Calas, Anca Nica, Y. Denoyer, M. Yochum, F. Wendling, P. Benquet

Network Neuroscience, 2024

Long-term Effect of Multichannel tDCS Protocol in Patients with Central Cortex Epilepsies Associated with Epilepsia Partialis Continua.

M. Daoud, C. Durelle, A. Fierain, El Youssef N, F. Wendling, G. Ruffini, P. Benquet, F. Bartolomei

Brain Topography, 2024

Multiscale neuro-inspired models for interpretation of EEG signals in patients with epilepsy

Fabrice Wendling, Elif Koksal-Ersoz, Mariam Al-Harrach, M. Yochum, I. Merlet, G. Ruffini, F. Bartolomei, P. Benquet

Clinical Neurophysiology, 2024

NeoCOMM: A Neocortical Neuroinspired Computational Model for the Reconstruction and Simulation of Epileptiform Events

M. Al Harrach, M. Yochum, G. Ruffini, F. Bartolomei, P. Benquet, F. Wendling

bioRxiv, 2024

Transition to seizure in focal epilepsy: From SEEG phenomenology to underlying mechanisms

Mehmet Alihan Kayabas, E. Köksal Ersöz, M. Yochum, F. Bartolomei, P. Benquet, Fabrice Wendling

Epilepsia, 2024

Improving Fast Ripples Recording With Model-Guided Design of Microelectrodes

M. A. Harrach, Gautier Dauly, H. Mousavi, Gabriel Dieuset, P. Benquet, Esma Ismailova, F. Wendling

IEEE Transactions on Biomedical Engineering, 2023

Signal processing and computational modeling for interpretation of SEEG-recorded interictal epileptiform discharges in epileptogenic and non-epileptogenic zones

Elif Köksal-Ersöz, Remo Lazazzera, M. Yochum, I. Merlet, J. Makhalova, B. Mercadal, R. Sanchez-Todo, G. Ruffini, F. Bartolomei, P. Benquet, F. Wendling

Journal of Neural Engineering, 2022

Spatio-temporal dynamics of large-scale electrophysiological networks during cognitive action control in healthy controls and Parkinson's disease patients

J. Duprez, Judie Tabbal, Mahmoud Hassan, J. Modolo, A. Kabbara, A. Mheich, S. Drapier, M. Vérin, P. Sauleau, F. Wendling, P. Benquet, Jean-François Houvenaghel

NeuroImage, 2022

Transcranial current stimulation in epilepsy: A systematic review of the fundamental and clinical aspects

Sara Simula, M. Daoud, G. Ruffini, M. Biagi, C. Bénar, P. Benquet, F. Wendling, F. Bartolomei

Frontiers in Neuroscience, 2022

An electroencephalography connectome predictive model of major depressive disorder severity

A. Kabbara, G. Robert, M. Khalil, M. Vérin, P. Benquet, Mahmoud Hassan

Scientific Reports, 2021

An individualized Neural Mass Model of ictal activity based on GABA-A pathology for personalization of brain stimulation protocols in epilepsy

E. Lopez-Sola, R. Sanchez-Todo, Èlia Lleal, Elif Köksal-Ersöz, M. Yochum, J. Makhalova, B. Mercadal, P. Benquet, F. Wendling, G. Ruffini

Brain Stimulation, 2021

Impaired dynamics of prefrontal beta-band networks during cognitive action control in Parkinson’s disease

J. Duprez, Judie Tabbal, Mahmoud Hassan, J. Modolo, A. Kabbara, A. Mheich, S. Drapier, M. Vérin, P. Sauleau, F. Wendling, P. Benquet, Jean-François Houvenaghel

bioRxiv, 2021

In silico model reveals the key role of GABA in KCNT1‐epilepsy in infancy with migrating focal seizures

M. Kuchenbuch, R. Nabbout, M. Yochum, P. Sauleau, J. Modolo, F. Wendling, P. Benquet

Epilepsia, 2021

Long term evolution of fast ripples during epileptogenesis

M. A. Harrach, P. Benquet, F. Wendling

Journal of Neural Engineering, 2021

Dynamics of task-related electrophysiological networks: a benchmarking study

Judie Tabbal, A. Kabbara, M. Khalil, P. Benquet, Mahmoud Hassan

NeuroImage, 2020

Modelling acute and lasting effects of tDCS on epileptic activity

Y. Denoyer, I. Merlet, F. Wendling, P. Benquet

Journal of Computational Neuroscience, 2020

Biophysical Modeling for Brain Tissue Conductivity Estimation Using SEEG Electrodes

Andrés Carvallo, J. Modolo, P. Benquet, S. Lagarde, F. Bartolomei, F. Wendling

IEEE Transactions on Biomedical Engineering, 2019

Decoding the circuitry of consciousness: From local microcircuits to brain-scale networks

J. Modolo, Mahmoud Hassan, F. Wendling, P. Benquet

Network Neuroscience, 2019

Detecting transient brain states of functional connectivity: A comparative study

Judie Tabbal, A. Kabbara, M. Khalil, Mahmoud Hassan, P. Benquet

2019 Fifth International Conference on Advances in Biomedical Engineering (ICABME), 2019

KCNT1 epilepsy with migrating focal seizures shows a temporal sequence with poor outcome, high mortality and SUDEP.

M. Kuchenbuch, G. Barcia, N. Chemaly, Emilie Carme, A. Roubertie, M. Gibaud, P. van Bogaert, A. De Saint Martin, E. Hirsch, Fanny Dubois, C. Sarret, S. Nguyen The Tich, C. Laroche, V. des Portes, T. Billette de Villemeur, M. Barthez, S. Auvin, N. Bahi-Buisson, I. Desguerre, A. Kaminska, P. Benquet, R. Nabbout

Brain : a journal of neurology, 2019

Dynamic reshaping of functional brain networks during visual object recognition

J. Rizkallah, P. Benquet, A. Kabbara, O. Dufor, F. Wendling, Mahmoud Hassan

Journal of Neural Engineering, 2018

On the origin of epileptic High Frequency Oscillations observed on clinical electrodes

M. Shamas, P. Benquet, I. Merlet, M. Khalil, W. Falou, Anca Nica, F. Wendling

Clinical Neurophysiology, 2018

Physiological effects of low-magnitude electric fields on brain activity: advances from in vitro, in vivo and in silico models.

J. Modolo, Y. Denoyer, F. Wendling, P. Benquet

Current Opinion in Biomedical Engineering, 2018

Quantitative analysis and EEG markers of KCNT1 epilepsy of infancy with migrating focal seizures

M. Kuchenbuch, P. Benquet, A. Kaminska, A. Roubertie, Emilie Carme, A. De Saint Martin, E. Hirsch, Fanny Dubois, C. Laroche, G. Barcia, N. Chemaly, M. Milh, N. Villeneuve, P. Sauleau, J. Modolo, F. Wendling, R. Nabbout

Epilepsia, 2018

SEEG Recordings: From Signal Processing to Models of Epileptogenic Networks

F. Wendling, P. Benquet, F. Bartolomei

Invasive Studies of the Human Epileptic Brain, 2018

Functional connectivity disruptions correlate with cognitive phenotypes in Parkinson's disease

Mahmoud Hassan, L. Chaton, P. Benquet, A. Delval, C. Leroy, L. Plomhause, A. Moonen, A. Duits, A. Leentjens, V. V. Kranen-Mastenbroek, L. Defebvre, P. Derambure, F. Wendling, K. Dujardin

NeuroImage: Clinical, 2017

Long term outcome of patients with Epilepsy with migrating focal seizure in infancy (EMFSI) due to KCNT1 mutation

M. Kuchenbuch, A. Kaminska, N. Chemaly, M. Gibaud, A. D. S. Martin, Fanny Dubois, C. Sarret, F. Wendling, P. Benquet, R. Nabbout

2017

A New Computational Model for Neuro-Glio-Vascular Coupling: Astrocyte Activation Can Explain Cerebral Blood Flow Nonlinear Response to Interictal Events

Solenna Blanchard, Sandrine Saillet, A. Ivanov, P. Benquet, C. Bénar, M. Pélégrini-Issac, H. Benali, F. Wendling

PLoS ONE, 2016

Brain (Hyper)Excitability Revealed by Optimal Electrical Stimulation of GABAergic Interneurons

F. Wendling, U. Gerber, D. Cosandier-Rimélé, A. Nica, J. Montigny, O. Raineteau, S. Kalitzin, F. L. D. Silva, P. Benquet

Brain Stimulation, 2016

Computational models of epileptiform activity

F. Wendling, P. Benquet, F. Bartolomei, Viktor Jirsa

Journal of Neuroscience Methods, 2016

Dynamic changes of depolarizing GABA in a computational model of epileptogenic brain: Insight for Dravet syndrome

Polina Kurbatova, Fabrice Wendling, Anna Kaminska, Anna Rosati, Rima Nabbout, Renzo Guerrini, O. Dulac, Gérard Pons, Catherine Cornu, Patrice Nony, C. Chiron, P. Benquet

Experimental Neurology, 2016

Dynamic reorganization of functional brain networks during picture naming

Mahmoud Hassan, P. Benquet, A. Biraben, C. Berrou, O. Dufor, F. Wendling

Cortex, 2015

Distinct hyperexcitability mechanisms underlie fast ripples and epileptic spikes

S. Demont-Guignard, P. Benquet, U. Gerber, A. Biraben, Benoît Martin, F. Wendling

Annals of Neurology, 2012

Neuron to Astrocyte Communication via Cannabinoid Receptors Is Necessary for Sustained Epileptiform Activity in Rat Hippocampus

G. Coiret, J. Ster, B. Grewe, F. Wendling, F. Helmchen, U. Gerber, P. Benquet

PLoS ONE, 2012

Energy deprivation transiently enhances rhythmic inhibitory events in the CA3 hippocampal network in vitro

C. Gee, P. Benquet, S. Demont-Guignard, F. Wendling, U. Gerber

Neuroscience, 2010

Metabotropic glutamate receptors: intracellular signaling pathways.

U. Gerber, C. Gee, P. Benquet

Current opinion in pharmacology (Print), 2007

Energy deprivation induces network oscillations in the CA3 subfield of organotypic hippocampal slice cultures

C. Gee, P. Benquet, U. Gerber

2005

Muscarinic receptor stimulation reduces NMDA responses in CA3 hippocampal pyramidal cells via Ca2+-dependent activation of tyrosine phosphatase

A. Grishin, P. Benquet, U. Gerber

Neuropharmacology, 2005

Differential Calcium-Dependent Modulation of NMDA Currents in CA1 and CA3 Hippocampal Pyramidal Cells

A. Grishin, C. Gee, U. Gerber, P. Benquet

Journal of Neuroscience, 2004

Group I metabotropic glutamate receptors activate a calcium‐sensitive transient receptor potential‐like conductance in rat hippocampus

C. Gee, P. Benquet, U. Gerber

Journal of Physiology, 2003

Two Distinct Signaling Pathways Upregulate NMDA Receptor Responses via Two Distinct Metabotropic Glutamate Receptor Subtypes

P. Benquet, C. Gee, U. Gerber

Journal of Neuroscience, 2002